Acute leukemia in children with Down syndrome
نویسندگان
چکیده
Department of Pediatrics, Medical University of South Carolina, Charleston, SC, USA. Division of Pediatric Hematology/Oncology, Children's Hospital of Michigan, Detroit, MI, USA. Developmental Therapeutics Program, Barbara Ann Karmanos Cancer Institute, Detroit, MI, USA. Department of Pediatrics, Wayne State University School of Medicine, Detroit, MI, USA. E-mail: [email protected]. doi:10.3324/haematol.2010.024968
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Although leukemia is the most common malignancy in childhood, congenital leukemia which manifests itself within the first 4 weeks of life is rare and accounts for less than 1% of all leukemias in childhood. Congenital leukemia should be differentiated from transient myeloproliferative disorder(TMD) which is noted in Down Syndrome. Among the reported patients, acute myeloid leukemia(AML) was...
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